Taurine increases bile acid pool size and reduces bile saturation index in the hamster
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منابع مشابه
Taurine increases bile acid pool size and reduces bile saturation index in the hamster.
There is evidence that increased availability of taurine enhances the proportion of taurine-conjugated bile acids in bile. To explore the possibility that taurine treatment could also influence hepatic cholesterol and bile acid metabolism, we fed female hamsters for 1 week and measured both the biliary lipid content and the microsomal level of the rate-limiting enzymes of cholesterol and bile a...
متن کاملTaurine increases bile acid pool size and reduces bile saturation index in the hamster1
There is evidence that increased availability of taurine enhances the proportion of taurine-conjugated bile acids in bile. To explore the possibility that taurine treatment could also influence hepatic cholesterol and bile acid metabolism, we fed female hamsters for 1 week and measured both the biliary lipid content and the microsomal level of the rate-limiting enzymes of cholesterol and bile a...
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Intraluminal concentrations of bile acids are low in newborn infants and increase rapidly after birth, at least partly owing to increased bile acid synthesis rates. The expansion of the bile acid pool is critical since bile acids are required to stimulate bile flow and absorb lipids, a major component of newborn diets. The purpose of the present studies was to determine the mechanism responsibl...
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In patients with cholesterol gallstones, there is a diminished bile acid pool and the bile becomes supersaturated with cholesterol. Medical treatment has been aimed at re-expanding the pool to improve cholesterol solubility in bile but as yet the factors controlling the size of the bile acid pool' are unknown. Therefore the role of the liver and intestine in controlling bile acid pool size in t...
متن کاملThe effect of bile acid structure on the activity of bile acid-CoA:glycine/taurine-N-acetyltransferase.
Bile acid-CoA:glycine/taurine N-acetyltransferase from bovine liver was analyzed for its ability to conjugate a variety of different bile acid-CoA analogues. A complete steady state bisubstrate kinetic analysis was conducted for each analogue. The enzyme demonstrated strict specificity for the normal 4-substituted pentanoic acid side chain; shortening the side chain by 1 methylene group (norcho...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1987
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)38617-x